Title of article :
MMP-9 IN FOLLICULAR FLUID IN PCO NON PCO FEMALES UNDERGOING ICSI
Author/Authors :
El Kassar, Yasser Alexandria Fertility Center - Department of Obstetrics and Gynaecology, Egypt , Swelem, Manal Alexandria University - Alexandria Fertility Center - Department of Obstetrics and Gynaecology, Egypt , Sallam, Hassan Alexandria Fertility Center - Department of Obstetrics and Gynaecology, Egypt , El Samra, Mohamed Alexandria Fertility Center - Department of Obstetrics and Gynaecology, Egypt , Swelem, Rania Alexandria University - Department of Clinical Pathology, Egypt
Abstract :
Background: Matrix Metalloproteinase-9 (MMP-9) is a proteolytic enzyme, the significance of which in the follicle maturation has been widely studied in non-stimulated animal models and humans. Aim: To compare the level of this enzyme in follicular fluid in PCO (polycystic ovary) and non PCO females undergoing intracytoplasmic sperm injection (ICSI). Methods: MMP-9 was measured in the follicular fluid in 20 PCO and 30 non PCO females undergoing ICSI. Results: Total MMP-9 showed no statistically significant difference between the two groups (p= 0.145).While, MMP-9 per oocyte showed a statistically significant difference between the two groups, (p = 0.001). So MMP-9 per oocyte is greater in non PCO group. Conclusions: There is no difference between MMP-9 secretion in follicular fluid in PCO and non PCO females undergoing ICSI.
Keywords :
MMP , 9 , follicular fluid , PCO , ICSI.
Journal title :
Alexandria Journal of Medicine(AJM)
Journal title :
Alexandria Journal of Medicine(AJM)
