Title of article :
EMERGING MOLECULAR APPROACHES AND THEIR SIGNIFICANCE IN THE DIAGNOSIS AND MANAGEMENT OF HEPATITIS C VIRUS INFECTION
Author/Authors :
Naz, Sumera National Institute of Health - PMRC Central Research Center, Pakistan , Bhatti, Attya National Institute of Health - PMRC Central Research Center, Pakistan , Khan, Mohammad Shoaib Bannu Medical College - Department of Biochemistry, Pakistan
Abstract :
Molecular biology based assays are invaluable tools for the diagnosis and management of chronic viral hepatitis. They can be used to test donor’s blood, to diagnose active infection, guide treatment deci- sions, assess the virological response to therapy and establish the prognosis. For hepatitis C infection, these include serological assays for anti-HCV antibody detection and molecular assays that detect and quantify HCV-RNA and determine the HCV genotype. This article reviews the current molecular biology based techniques and assays and their practical use in the management of hepatitis C virus infection.
Keywords :
Hepatitis C , Molecular Biology Assay , Genotype.
Journal title :
GOMAL JOURNAL OF MEDICAL SCIENCES
Journal title :
GOMAL JOURNAL OF MEDICAL SCIENCES
