Author/Authors :
Zare Zardini, Hadi Shahid Sadoughi university of Medical Sciences and Health Services - Genetics Research Center - Department of Pediatrics, Hematology, Oncology, ايران , Zare Zardini, Hadi Islamic Azad University, Yazd Branch - Young Researchers Club, ايران , Tolueinia, Behnaz ferdowsi university of mashhad - Faculty of Sciences - Department of Chemistry, مشهد, ايران , Momeni, Zeinab ferdowsi university of mashhad - Faculty of Sciences - Department of Biology, مشهد, ايران , Hasani, Zohre ferdowsi university of mashhad - Faculty of Sciences - Department of Biology, مشهد, ايران , Hasani, Masumeh payame noor university, تهران, ايران
Abstract :
Background: Antimicrobial compounds with plant sources have numerous therapeutic potentials; not only are they effective in the treatment of infectious diseases, but also have less chances of side-effects often associated with antimicrobial compounds. This study was conducted to evaluate the antimicrobial activity of coriander seed extract. Material Methods: Extraction from seed of plant was carried out through maceration. Then antibacterial and antifungal activity of extract was done with Radial Diffusion Assay method. Minimum inhibitory concentration of this extract was also determined. Results: The results demonstrated a wide antimicrobial activity of the extract against the microbes studied. Antimicrobial effects of the plant extract showed the greatest effect on Staphylococcus aureus resistant strain. Plant extract displayed also effective germicidal effects on Klebsiella pneumonia, Pseudomonas aeruginosa as well as Penicillium lilacinum and Asperjilus niger. Conclusion: Coriander seed extract has effective antimicrobial activity against gram-negative and gram-positive bacteria as well as fungi
