MATERNAL AND FETAL OUTCOME OF GESTATIONAL DIABETES MELLITUS

Background: Gestational diabetes mellitus is associated with increased risk of serious perinatla morbidities and mortalities, as well maternal morbidities. The objective of this study was to compare the maternal and fetal outcome of gestational disabetes mellitus with healthy pregnant women. Material Methods: This study was carried out in the Institute of Chemical Sciences, Peshawar University, Peshawar, Pakistan from February 2012 to December 2012. One hundred and thirty ladies with gestational diabetes mellitus and 97 healthy pregnant woman were registered and followed until delivery to know the maternal and fetal outcome. Results: Regarding maternal complications; Women with gestational diabetes were more prone to pregnancy induced hypertension (22.3% vs 11.3%, p 0.05), pre-eclampsia (16.5% vs 6.2%, p=0.02), premature rupture of membranes (19.4% vs 5.15%, P=0.002), preterm labor (25.2% vs 8.23%, p=0.001) and ceasarean delivery (23.3% vs 12.4%, p=0.009) as compared to controls. Regarding neonatal complications; there was increased risk of macrosomia (28.2% vs 10.3%, p=0.001), shoulder dystocia or birth trauma (27.2% vs 6.2%, p 0.001) and jaundice (29.1% vs 10.3%, p=0.001). Congenital anomalies were not significantly higher in women with gestational diabetes