Title of article :
Selected Abstracts Presented at IRSOT 2013 Congress
Author/Authors :
Fonouni, H. University of Heidelberg - Department of General, Visceral and Transplantation Surgery, Germany , Golriz, M. University of Heidelberg - Department of General, Visceral and Transplantation Surgery, Germany , Hafezi, M. University of Heidelberg - Department of General, Visceral and Transplantation Surgery, Germany , Mehrabi, A. University of Heidelberg - Department of General, Visceral and Transplantation Surgery, Germany
Abstract :
Background: Patients with polycystic kidney disease (PKD) are candidates for kidney transplantation (KTx).
Objective: To report the results of our single-center case series of the first KTx in 250 PKD patients with autosomal dominant (64%), medullary cystic (16%), autosomal recessive (6%), and non-specified (14%) form
of the disease.
Methods: The peri-transplantation data were analyzed according to the origin of the graft (deceased donor:
DD, and living donor: LD). We analyzed demographic data of donors and recipients, waiting time, duration
of dialysis, transfusion, nephrectomy, hospital stay, morbidities, and graft and patient survival.
Results: The DD group consisted of 79% and LD group 21% of the patients. Nephrectomy was performed on
21% of the recipients. The DD group had a significantly higher rate of hemodialysis (82% vs. 68%), duration
of dialysis (1571 vs. 1002 days), waiting time (1129 vs. 33 days), and blood transfusions (45% vs. 27%) than
the LD group. Surgical complications included arterial stenosis (1% in DD vs. nil in LD), venous thrombosis
(1% in DD vs. nil in LD), urine leakage (0.5% in DD vs. 1.9% in LD), ureteral stenosis (0.5% in DD vs. nil in
LD), reflux (nil in DD vs. 1.9% in LD), lymphocele (11.7% in DD vs. 8.1% in LD) and hernia (5.2% in DD vs.
8.1% in LD) with no significant difference. The graft and patient survival rates were similar in both studied
groups.
Conclusion: The low rate of morbidity along with excellent survival rates makes KTx an excellent option for
PKD patients. Although fear of future appearance of PKD may reduce the rate of related LD, we showed better outcome after LD in terms of graft and patient survival.
Keywords :
Selected Abstracts Presented , IRSOT 2013 Congress
Journal title :
International Journal of Organ Transplantation Medicine
Journal title :
International Journal of Organ Transplantation Medicine