Title of article :
IN VITRO ANTIOXIDANT ACTIVITY OF LAGENARIA SICERARIA LEAVES
Author/Authors :
SHARMA, NEERAJ KANT Suresh Gyan Vihar University - Gyan Vihar School of Pharmacy, India , YADAV, PRIYANKA Teerthanker Mahaveer University - College of Pharmacy, India , SINGH, HEMANT KUMAR Mahatma Gandhi Institute of Pharmacy, India , SHRIVASTAVA, ANIL KUMAR National Institute of Medical Sciences University - Institute of Pharmacy, India
Abstract :
The free radical scavenging potential of methanolic extract of Lagenaria siceraria leaves (MELS) was studied on in vitro antioxidant models. The antioxidant potential was evaluated by determining the activity of hydroxyl and hydrogen peroxide (H2O2) radicals scavenging and 1,1-diphenyl-2-picryl hydrazyl (DPPH) assay. In all these studies, a significant correlation existed between concentrations of the extract and percentage inhibition of free radicals. The extract was also shown to have high phenolic content i.e. 99.09±0.10 μg/mg. These results clearly indicated that MELS could be a potential source of natural antioxidant and effective against free radical mediated diseases
Keywords :
Antioxidant , In vitro , Lagenaria siceraria , Reactive oxygen species
Journal title :
Malaysian Journal of Pharmaceutical Sciences
Journal title :
Malaysian Journal of Pharmaceutical Sciences
