Title of article
Vitiligo: new etiology-based treatments
Author/Authors
Hameed, Abdul King Edward Medical College - Mayo Hospital - Department of Dermatology Unit-I, Pakistan , Rani, Zahida Mayo Hospital - King Edward Medical College - Dermatology Department, Unit I, Pakistan , Kazmi, Atif Hasnain Mayo Hospital - King Edward Medical College - Department of Dermatology, Pakistan
From page
252
To page
260
Abstract
Vitiligo is an acquired depigmentary disorder characterized by a chronic and progressive loss of melanocytes from the epidermis. The etiopathogenesis of vitiligo is still not fully understood, and the major theories include melanocyte destruction (autoimmune, neural and impaired redox status) and melanocyte inhibition or defective adhesion. Recently a new theory, melanocytorrhagy, was forwarded. In this review are also discussed the new etiology- based treatments, mainly topical calcipotriol, topical immunomodulators and topical catalase.
Keywords
vitiligo , calcipotriol , tacrolimus , pimecrolimus , catalase.
Journal title
Journal of Pakistan Association of Dermatologists
Journal title
Journal of Pakistan Association of Dermatologists
Record number
2573512
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