Author/Authors :
Shome, Kaushik Medical College and Hospital - Department of Dermatology, Venereology and Leprology, India , Samanta, Asit Baran Medical College and Hospital - Department of Dermatology, Venereology and Leprology, India , Halder, Saswati Medical College and Hospital - Department of Dermatology, Venereology and Leprology, India , Seth, Joly Medical College and Hospital - Department of Dermatology, Venereology and Leprology, India , Mandal, B.K. Medical College and Hospital - Department of Dermatology, Venereology and Leprology, India , Sarkar, Prodip Medical College and Hospital - Department of Dermatology, Venereology and Leprology, India
Abstract :
Extramammary Paget’s disease (EMPD) is a rare neoplasm with only a limited number of reported cases in literature. It is mainly composed of intraepidermal Paget cells and possesses variable clinical behaviour and histological appearance leading to difficulty in diagnosis. We here report a case of primary EMPD in a 71-year-old male who presented with gradually progressive, pruritic, eczematous lesion in suprapubic region, not responding to topical medications. Histological assessment showed Paget cells infiltration throughout the epidermis with dermal invasion. Using immunohistochemistry, the expression of CK7, carcinoembryonic antigen (CEA) was examined to elucidate cellular differentiation of the carcinoma.
Keywords :
Suprapubic region , Paget’s cells , cytokeratin 7 , carcinoembryonic antigen.
