Title of article :
Synchronous Hepatocellular Carcinoma and Cholangiocellular Carcinoma on 18F-FDG PET/CT
Author/Authors :
Aydın, Mehmet Bezmialem Vakıf University Faculty of Medicine - Department of Nuclear Medicine - İstanbul, Turkey , Erdoğan, Ezgi Başak Bezmialem Vakıf University Faculty of Medicine - Department of Nuclear Medicine - İstanbul, Turkey , Türk, Hacı Mehmet Bezmialem Vakıf University Faculty of Medicine - Department of Medical Oncology - İstanbul, Turkey , Tekçe, Ertuğrul Bezmialem Vakıf University Faculty of Medicine - Department of Radiation Oncology - İstanbul, Turkey
Abstract :
A 43-year-old male patient presented with a mass lesion on the right liver lobe, segment 5, in radiological imaging and elevated alpha-fetoprotein levels (323 ng/mL) compatible with hepatocellular carcinoma (HCC). Positron emission tomography/computed tomography (PET/CT) images showed background level 18F-FDG uptake in the mass lesion. In addition, a secondary focus of increased 18F-FDG uptake was detected on the left liver lobe, segment 2, approximately 1,5 cm in diameter. Histopathological examination revealed HCC in the larger mass lesion with a lower 18F-FDG uptake, and cholangiocellular carcinoma in the smaller mass lesion with a higher 18F-FDG uptake. To our knowledge, this is the first case report of two histopathologically different primary malignant liver tumors in two distinct segments of the liver detected by PET/CT.
Keywords :
18F-FDG PET/CT , cholangiocellular carcinoma , hepatocellular carcinoma , Synchronous tumors
Journal title :
Molecular Imaging and Radionuclide Therapy
