Title of article :
Disseminated Multi-system Sarcoidosis Mimicking Metastases on 18F-FDG PET/CT
Author/Authors :
Makis, William Cross Cancer Institute - Department of Diagnostic Imaging - Edmonton, Canada , Palayew, Mark Jewish General Hospital - Department of Nuclear Medicine - Montreal, Canada , Rush, Christopher Jewish General Hospital - Department of Nuclear Medicine - Montreal, Canada , Probst, Stephan Jewish General Hospital - Department of Nuclear Medicine - Montreal, Canada
Abstract :
A 60-year-old female with no significant medical history presented with hematuria. A computed tomography (CT) scan revealed extensive lymphadenopathy with hypodensities in the liver and spleen, and she was referred for an 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography/CT (PET/CT) study to assess for malignancy of unknown primary. PET/CT revealed extensive 18F-FDG avid lymphadenopathy as well as innumerable intensely 18F-FDG avid lung, liver and splenic nodules, highly concerning for malignancy. A PET-guided bone marrow biopsy of the posterior superior iliac spine revealed several non-necrotizing, well-formed granulomas, consistent with sarcoidosis. The patient was managed conservatively and remained clinically well over the subsequent 9 years of follow-up.
Keywords :
positron emission tomography , 18F-fluorodeoxyglucose , lymphadenopathy , artifact mimic , metastases , Sarcoidosis
Journal title :
Molecular Imaging and Radionuclide Therapy
