Title of article :
Polymer Modified Carbon Paste Electrode as a Sensitive Sensor for the Electrochemical Determination of Riboflavin and Its Application in Pharmaceutical and Biological Samples
Author/Authors :
Souza, Edwin S D’ Department of chemistry - FMKMC College - Madikeri - Constituent College of Mangalore University, Karnataka, India - Department of Chemistry - St. Philomena College - Puttur, Karnataka, India , Manjunatha, J.G Department of chemistry - FMKMC College - Madikeri - Constituent College of Mangalore University, Karnataka, India , Raril, C. Department of chemistry - FMKMC College - Madikeri - Constituent College of Mangalore University, Karnataka, India , Tigari, Girish Department of chemistry - FMKMC College - Madikeri - Constituent College of Mangalore University, Karnataka, India , Pushpanjali, P.A. Department of chemistry - FMKMC College - Madikeri - Constituent College of Mangalore University, Karnataka, India
Pages :
12
From page :
461
To page :
472
Abstract :
Poly (threonine) modified carbon paste electrode (PTMCPE) can be used as a responsive and selective electrocatalytic sensor for the estimation of riboflavin (RF) by means of cyclic voltammetry (CV) and differential pulse voltammetry (DPV). The proposed electrode creates a catalytic enhancement in redox behavior of RF when equated with bare carbon paste electrode (BCPE). Under optimized conditions, RF quantification at modified electrode has shown a detection limit of 1.78 × 10-7 M in the linear range of 0.2-1 μM and 1-5 μM. Simultaneous analysis of RF with folic acid (FA) and ascorbic acid (AA) shows well-separated peaks leading to a quick and selective analysis of RF. The fabricated sensor can be successfully applied to RF analysis in human blood serum and B- complex tablet with acceptable results.
Keywords :
Riboflavin , Electrochemical sensor , Carbon paste electrode , Poly (threonine) , Ascorbic acid , Folic acid
Journal title :
Analytical and Bioanalytical Chemistry Research
Serial Year :
2020
Record number :
2575018
Link To Document :
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