Author/Authors :
Pignalosa, Orlando Azienda Ospedaliera Universitaria, Second University of Naples - Clinical Immunology, Immunohematology, Transfusion Medicine and Transplant Immunology - Unità Operativa Complessa, Regional Reference Laboratory of Transplant Immunology, Department of Internal Medicine and Specialistic Unit, Italy , Martusciello, Dario Second University of Naples - Multidisciplinary Department of Medical-Surgical and Odontostomatological Specialties, Italy , De Pascale, Maria R. Azienda Ospedaliera Universitaria, Second University of Naples - Clinical Immunology, Immunohematology, Transfusion Medicine and Transplant Immunology - Unità Operativa Complessa, Regional Reference Laboratory of Transplant Immunology, Department of Internal Medicine and Specialistic Unit, Italy , Sommese, Linda Azienda Ospedaliera Universitaria, Second University of Naples - Clinical Immunology, Immunohematology, Transfusion Medicine and Transplant Immunology - Unità Operativa Complessa, Regional Reference Laboratory of Transplant Immunology, Department of Internal Medicine and Specialistic Unit, Italy , Nicoletti, Giovanni F. Second University of Naples - Multidisciplinary Department of Medical-Surgical and Odontostomatological Specialties, Italy , Itro, Angelo Second University of Naples - Multidisciplinary Department of Medical-Surgical and Odontostomatological Specialties, Italy , Cavalca, Francesco Azienda Ospedaliera Universitaria, Second University of Naples - Clinical Immunology, Immunohematology, Transfusion Medicine and Transplant Immunology - Unità Operativa Complessa, Regional Reference Laboratory of Transplant Immunology, Department of Internal Medicine and Specialistic Unit, Italy , Tartaro, Gianpaolo Second University of Naples - Multidisciplinary Department of Medical-Surgical and Odontostomatological Specialties, Italy , Napoli, Claudio Azienda Ospedaliera Universitaria, Second University of Naples - Clinical Immunology, Immunohematology, Transfusion Medicine and Transplant Immunology - Unità Operativa Complessa, Regional Reference Laboratory of Transplant Immunology, Department of Internal Medicine and Specialistic Unit, Italy
Abstract :
Objective: To report on the clinical benefits of platelet gel application in a non-regenerating skin wound. Clinical Presentation and Intervention: An 84-year-old man presented with a severe wound with a regular circumference in the frontal region which resulted in a complete loss of epidermis and dermis. The skin lesion, induced by cryosurgery used to remove a basal-cell carcinoma, had previously been treated with a dermal substitute application (Integra ® ). After the failure of the skin graft, the patient was treated using a platelet gel therapeutic protocol which achieved the complete healing of the injured area. Conclusion: This case showed the clinical efficacy of using platelet gel in this elderly patient in whom the dermal substitute graft had been ineffective.