Tissue engineered human heart valves

The is no ideal heart valve substitute, both mechanical and biologic heart valve have significant limitation in term of durability, growth potential (for infant and children), compatibility, resistance to infection(1).Tissue-engineered heart valve have been proposed by physicians and scientists alike to be the ultimate solution for treating valvular heart disease rather than replacing a diseased or defective native valve with a mechanical or bioprosthesis, a tissue engineered valve would be a living organ with the capability for growth, repair and remodeling in the same way that the native heart valve does.Over the last decade attempts to create tissue engineered heart valve have been made with varying degrees of success, constructing these valve from a Varity of cell types and scaffolding materials. Early results in animals and limited clinical application are promising although it will take many years to demonstrate that long-term performance of this valve is comparable or better than conventional prosthetic heart valve