Title of article :
Antioxidant Activity of Two Mesomeric Heterocyclic Betaines Containing a Pyrimidine Moiety
Author/Authors :
Malki, F. Ecole Normale Supérieure - Laboratoire de Recherche sur les Produits Bioactifs et Valorisation de la Biomasse, Algeria , Touati, A. Ecole Normale Supérieure - Laboratoire de Recherche sur les Produits Bioactifs et Valorisation de la Biomasse, Algeria , Moulay, S. Université Saâd Dahlab de Blida - Faculté de Technologie - Département de Chimie Industrielle, Laboratoire de Chimie-Physique Moléculaire et Macromoléculaire, Algeria
Abstract :
Two mesomeric heterocyclic betaines, phenyl pyrimidinium betaine (BT1) and undecyl pyrimidinium betaine (BT2), were investigated for their antioxidant activity using the 2, 2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging assay. The antioxidant propriety was assessed by the effective concentration of the betaine (EC50), the time required to reach the steady state of DPPH discoloration at EC50 concentration (TEC50), the antiradical efficiency (AE), and the reduction kinetics. Vitamin E (α-tocopherol) and ditert- butylhydroxytoluene (BHT) were used as the standard antioxidants in in vitro assays. Kinetic studies showed that BT1 was more effective than vitamin E and BT2.
Keywords :
etaine , pyrimidine , antioxidant , DPPH assay , reduction kinetic
Journal title :
Pertanika Journal of Tropical Agricultural Science (JTAS)
Journal title :
Pertanika Journal of Tropical Agricultural Science (JTAS)