Title of article :
Kikuchi Disease with Generalized Lymph Node, Spleen and Subcutaneous Involvement Detected by Fluorine-18-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography
Author/Authors :
Ashkanani, Rasha Mubarak Al Kabeer Hospital - Clinic of Nuclear Medicine - Jabriya, Kuwait , Alshammari, Alshaima Mubarak Al Kabeer Hospital - Clinic of Nuclear Medicine - Jabriya, Kuwait , Kazem, Nafisa Mubarak Al Kabeer Hospital - Clinic of Nuclear Medicine - Jabriya, Kuwait , Skoura, Evangelia University College London Hospital - Clinic of Nuclear Medicine - London, United Kingdom
Abstract :
Kikuchi-Fujimoto disease, known as Kikuchi disease, is a rare benign and self-limiting disorder that typically affects the regional cervical lymph nodes. Generalized lymphadenopathy and extranodal involvement are rare. We report a rare case of a 19-year-old female with a history of persistent fever, nausea, and debilitating malaise. Fluorine-18-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) revealed multiple hypermetabolic generalized lymph nodes in the cervical, mediastinum, axillary, abdomen and pelvic regions with diffuse spleen, diffuse thyroid gland, and focal parotid involvement, bilaterally. In addition, subcutaneous lesions were noted in the left upper paraspinal and occipital regions. An excisional lymph node biopsy guided by 18F-FDG PET/CT revealed the patient’s diagnosis as Kikuchi syndrome.
Keywords :
fluorine-18-fluorodeoxyglucose , histiocytic necrotizing lymphadenitis , Kikuchi-Fujimoto disease
Journal title :
Molecular Imaging and Radionuclide Therapy
