Title of article :
Programming of Fe-catalyzed cascade Knoevenagel-Michael-cyclocondensation reaction: create out pseudo acridine derivatives under solvent free conditions
Author/Authors :
Khazaei ، Ardeshir Bu-Ali Sina University , Moosavi-Zare ، Ahmad Reza Department of Chemistry - University of Sayyed Jamaleddin Asadabadi , Afshar-Hezarkhani ، Hadis Faculty of Chemistry - Bu-Ali Sina University , Khakyzadeh ، Vahid Department of Chemistry - K. N. Toosi University of Technology
Abstract :
Nano-ferrous ferric oxide (nano-Fe3O4) was successfully applied as an efficient and heterogeneous catalyst for the synthesis of 1,8-dioxo-decahydroacridines by the condensation reaction of dimedone with aromatic aldehydes and ammonium acetate or aniline derivatives under mild and solvent-free conditions. Also, optimization of the reaction condition was investigated using the response surface method {Central Composite Design (CCD)} compared to empirical research.
Keywords :
Nano , Fe3O4 , Cascade reaction , 1 , 8 , dioxo , decahydroacridine , Heterogeneous catalyst
Journal title :
Eurasian Chemical Communications
Journal title :
Eurasian Chemical Communications
