Title of article :
Simultaneous electrochemical determination of epinephrine and acetylcholine using modified screen printed electrode
Author/Authors :
Aflatoonian ، Mohammad Reza Neuroscience Research Center, Leishmaniasis Research Center - Kerman University of Medical Sciences , Tajik ، Somayeh Neuroscience Research Center, Research Center for Tropical and Infectious Diseases - Kerman University of Medical Sciences , Aflatoonian ، Behnaz Neuroscience Research Center - Kerman University of Medical Sciences , Ekrami-Kakhki ، Mehri-Saddat Esfarayen University of Technology , Alizadeh ، Reza Department of Chemistry - Faculty of Science - Qom University
Abstract :
Electrochemical behaviors of epinephrine and acetylcholine were investigated, using cyclic voltammetry, on the Ag-ZnO modified screenprinted electrode (Ag-ZnO/SPE). Ag-ZnO nanoplates showed excellent electrocatalytic activity toward the oxidation of epinephrine and acetylcholine compared with bare SPE in 0.1 M PBS. Under the optimized experimental conditions, a linear response obtained in the range of 0.13 to 450.00 μM with detection limit of 0.04 μM for epinephrine. Ag-ZnO/SPE exhibits good stability, reproducibility and repeatability, and the method has been successfully applied for detection of epinephrine and acetylcholine in their pharmaceutical and biological samples with satisfactory recovery.
Keywords :
Epinephrine , Acetylcholine , Ag , ZnO nanoplates , Screen printed electrode.
Journal title :
Eurasian Chemical Communications
Journal title :
Eurasian Chemical Communications
