Title of article :
Phosphomolybdic acid immobilized chitosan/Fe3O4: an efficient catalyst for the N-alkylation of anilines
Author/Authors :
Ghanimati ، Mahdi Department of Chemistry - Islamic Azad University, Arak Branch , Abdoli-Senejani ، Masumeh Department of Chemistry - Islamic Azad University, Arak Branch , Bodaghifard ، Mohammad Ali Department of Chemistry - Faculty of Science - Arak University , Momeni Isfahani ، Tahere Department of Chemistry - Islamic Azad University, Arak Branch
Abstract :
In this work, phosphomolybdic acid immobilized on chitosan/Fe3O4 as a green catalyst was used for the Hofmann Nalkylation of aniline derivatives with alcohols. H3PMo12O40/chitosan/Fe3O4 (PMo/Chit/Fe3O4) was prepared from the phosphomolybdic acid, chitosan, and Fe3O4 MNPs. Several secondary amines were synthesized from primary arylamines with electron‐donating, electron‐withdrawing groups, and alcohols in good to excellent yields. The catalyst could be separated using an external magnet and recovered without reducing its catalytic activity. The optimization of the reaction conditions was evaluated using the response surface method (RSM), involving the BoxBehnken design matrix. The simple procedure, only one byproduct (i.e., water), good to excellent yields, easy separation of the catalyst, short reaction times, and environmentally benign conditions were some advantages of this method.
Keywords :
Hofmann N , alkylation , Heterogeneous catalyst , Heteropolyacids , Chitosan , Design of experiment , Green chemistry
Journal title :
Eurasian Chemical Communications
Journal title :
Eurasian Chemical Communications
