Author/Authors :
Osonuga, A University of Cape Coast - School of Medical Sciences, Ghana , Osonuga, OA Olabisi Onabanjo University,Remo-Campus - Departments of Pharmacology and Physiology, Nigeria , Osonuga, AA University of Cape Coast - Department of Nursing, Ghana , Osonuga, IO Olabisi Onabanjo University, Remo-Campus - Departments of Pharmacology and Physiology, Nigeria
Abstract :
HIV is a RNA retrovirus that causes progressive weakening of the host’s immune system increasing susceptibility to opportunistic infections. Antiretroviral drugs are currently used to manage the infection. This paper reviews the benefits and the toxicity associated with ARTs currently used in Ghana. Google search, PUBMED and Google scholar were used to gather information from different books, websites and peerreviewed journal articles. ARTs significantly improved the quality of life of people living with HIV/AIDS by increasing the CD4 count and reducing the viral load. ARTs have short and long term side effects which may be life threatening. Toxicity may vary from drug to drug and from one drug class to the other. We conclude that it is important to select a regimen that is not only effective but also safe. This requires consideration of not only the toxicity potential of an ARV regimen but also an individual patient’s underlying conditions, concomitant medications and history of drug intolerance
