Author/Authors :
SHAVAKHI, AHMAD isfahan university of medical sciences - Department of Internal Medicine, اصفهان, ايران , KHODADUSTAN, MAHSA isfahan university of medical sciences - Department of Internal Medicine, اصفهان, ايران , ZAFARGHANDI, MARYAM shahid beheshti university of medical sciences - Research Center of Gastroenterology and Hepatology, تهران, ايران , GACHKAR, LATIF shahid beheshti university of medical sciences - Research Center of Gastroenterology and Hepatology, تهران, ايران , FIROZI, MARYAM shahid beheshti university of medical sciences - Research Center of Gastroenterology and Hepatology, تهران, ايران , EHSANI ARDAKANI, MOHAMMAD JAVAD shahid beheshti university of medical sciences - Research Center of Gastroenterology and Hepatology, تهران, ايران , SOMI, MOHAMMAD HOSSEIN tabriz university of medical sciences - Liver and gastrointestinal diseases research center, تبريز, ايران , ANTIKCHI, MOHAMMAD HOSSEIN yazd shahid sadoghi university of medical sciences - Department of Internal Medicine, يزد, ايران , MASOODI, MOHSEN Bandar Abbas University of Medical Sciences - Department of Internal Medicine, ايران , ZAIL, MOHAMMAD REZA isfahan university of medical sciences - Department of Internal Medicine, اصفهان, ايران
Abstract :
BACKGROUND: Cirrhosis is terminal stage of many chronic liver diseases like hepatitis C and hepatitis B. In some studies the role of helicobacter pylori has been demonstrated in progress of cirrhosis and its complications, but none of the previous studies has investigated the role of socioeconomic conditions of patients in childhood period in this issue. METHODS: In a case-control study, we examined 100 cirrhotic patients due to hepatitis (49 hepatitis Band 51 hepatitis C patients) and 101 socioeconomically matched healthy controls presenting to Taleghani Hospital for IgG antibody to helicobacter pylori. RESULTS: IgG antibody to helicobacter pylori was present in 73% of cirrhotic patients and 52% of control group (P 0.003). Odds ratio for the presence of IgG antibody to helicobacter pylori in cirrhotic men comparing with healthy men was 3.2 (95%CI: 1.4-7.4). CONCLUSIONS: The relative frequency of IgG antibody to helicobacter pylori found to be higher in cirrhotic patients than in controls with regard to socioeconomic condition in childhood.
Keywords :
Cirrhosis , hepatitis C , hepatitis B , helicobacter pylori , liver disease
