Author/Authors :
Khosrojerdi, Hamid mashhad university of medical sciences - Addiction Research Center, Imam Reza Hospital, School of Medicine, ايران , Afshari, Reza mashhad university of medical sciences - Addiction Research Center, Imam Reza Hospital, School of Medicine, ايران , Mehrpour, Omid birjand university of medical sciences - Birjand Atherosclerosis and Coronary Artery Research Center, Medical Toxicology and Drug Abuse Research, Faculty of Medicine - Department of Clinical Toxicology and Forensic Medicine, ايران
Abstract :
The efficacy of oral activated charcoal (AC) for the adsorption of drugs and poisons has been widely described
in the literature [1]. AC can prevent systemic absorption
of drugs if administrated within 1–2 h of ingestion and
possibly longer after ingestion of sustained-release preparations or drugs that delay gastric emptying, such as
opioids or antimuscarinic drugs. Since routine use of AC
is discouraged [1], it is important to consider the risks
and benefits of AC on a drug-by-drug basis. This brings
us to the question of whether AC should be administrated to patients with tramadol overdose?