Poly(vinylpyridine) Supported Reagents: A Review

Polymer supported reagents have become the subject of considerable andincreasing interest as insoluble materials in the organic synthesis. The attachmentof the reagents to the insoluble macromolecular matrix can solve the problemsof tedious work-up, lability, toxicity, or unrecyclability often experienced with nonpolymericlow-molecular weight reagents. A literature survey shows that a review onpoly(vinylpyridine)-supported reagents is not available yet. This review will focus onthe implementation of methodologies for polymer supported reagents based onpoly(vinylpyridine) (PVPy), in the organic synthesis appeared in the literature until theyear of 2009. The aim is to distill the literature into three categories and to presenteach as a short table listing the functionalized polymers involved, along with theirrelevant applications as reagents. In the text, discussions on the structural and transformationof some typical polymeric reagents are given, although there is not detailedprocedure provided in the text about the synthesis of the polymers or their transformations.When appropriate, comparison between the behaviour of supported reagentsversus non-supported reagents is attempted. This review does not include the patentliterature.