Author/Authors :
Ahmed, Bilal Bolan Medical College - Department of Dermatology, Pakistan , Tareen, Muhammad Iqbal University of Baluchistan - CASVAB, Pakistan , Kumar, Ashok Isra University - Department of Pathology, Pakistan , Baloch, Saira Liaquat University of Medical and Health Sciences - Medical Research Centre, Pakistan , Rehman, Hazir University of Baluchistan - CASVAB, Pakistan , Mustafa, Zahid University of Baluchistan - CASVAB, Pakistan , Tareen, Abdul Malik University of Baluchistan - CASVAB, Pakistan
Abstract :
Objective: To evaluate the efficacy of combined therapy of meglumine antimoniate and cotrimoxazole in cutaneous leishmaniasis (CL). Methods: 180 patients with active lesions of CL, confirmed by fine needle aspiration cytology (FNAC) were treated with combined therapy of meglumine antimoniate (Glucantime) and cotrimoxazole (Septran) for 20 days. Results: Out of 180 patients, 160 (88.9%) were cured. A few patients reported nausea, vomiting, glossitis, skin rashes and folate deficiency. Conclusion: The combined therapy of meglumine antimoniate (Glucantime) and co-trimoxazole (Septran) is more effective than the previously reported combined therapies.
Keywords :
Cutaneous leishmaniasis , meglumine antimoniate , co , trimoxazole , combined therapy.
