Title of article :
Exposure to potassium carbonate emulsion induced nephro-toxicity in experimental animals
Author/Authors :
Akintunde, J.K University of Agriculture - College of Medicine - Department of Biochemistry, Nigeria , Opeolu, B.O University of Agriculture - Department of Environmental Management and Toxicology, Nigeria , Aina, O.O University of Ibadan - Faculty of Veterinary Medicine - Department of Veterinary Anatomy, Nigeria
Abstract :
The study investigated the possible toxic effects of potassium carbonate emulsion on some biomarkers of tissue damage in rabbits. Exposure of rabbits to potassium carbonate (K2C03) emulsion at 50mg/L and 100mg/L via oral drinking for 14 consecutive days caused significant increase in the creatinine and uric acid at 100mg/L by 48.6% and 126.3% respectively. Also, potassium carbonate (K2C03) emulsion significantly increased serum blood urea nitrogen (BUN) at 50mg/L and 100mg/L concentration. The results however suggested that potassium carbonate emulsion exposure via oral drinking could precipitate kidney damage.
Keywords :
Potassium carbonate emulsion , nephro , toxicity , serum metabolites
Journal title :
Jordan Journal of Biological Sciences
Journal title :
Jordan Journal of Biological Sciences