Title of article :
Screening of Terminalia bellirica Fruits Extracts for its Analgesic and Antipyretic Activities
Author/Authors :
Sharma, Uma Shankar Sir Madanlal Group of Institutions - Department of Pharmacy, India , Sharma, Umesh Kumar Sir Madanlal Group of Institutions - Department of Pharmacy, India , Singh, Abhishek Sir Madanlal Group of Institutions - Department of Pharmacy, India , Sutar, Niranjan Sir Madanlal Group of Institutions - Department of Pharmacy, India , Singh, Puspak Jyoti Sir Madanlal Group of Institutions - Department of Pharmacy, India
Abstract :
The study was designed to investigate the analgesic and antipyretic activities of ethanolic and aqueous extracts of Terminalia bellirica (family: Combrataceae) fruits (200 mg/kg, p.o.) in acetic acid-induced writhing, Eddy’s hot plate method and brewer s yeast-induced fever models in mice and rats. Both extracts showed a significant decrease in the number of the writhes in acetic acid-induced writhing and increase in paw licking time to heat stimuli in the hot plate method. Both extracts showed a significant inhibition of elevated body temperature when compared to corresponding control. The results suggested that the ethanolic and aqueous extracts possessed significant analgesic and antipyretic activities
Keywords :
Terminalia bellirica , analgesic activity , acetic acid , induced writhing , hot plate method , antipyretic activity , brewer’s yeast , induced fever model
Journal title :
Jordan Journal of Biological Sciences
Journal title :
Jordan Journal of Biological Sciences
