Title of article :
Synthetic Studies Towards Bis-Heterodimeric Netropsin Analogs
Author/Authors :
Al-Said, Naim H. Jordan University of Science and Technology - Faculty of Science and Arts - Department of Applied Chemical Sciences, Jordan , Shawakfeh, Khaled Q. Jordan University of Science and Technology - Faculty of Science and Arts - Department of Applied Chemical Sciences, Jordan
Abstract :
An expedient synthetic method has been developed for the preparation of a properly functionalized pyrrole-imidazole template suitable for the construction of heterodimeric bis- lexitropsins. The pyrrole-imidazole carboxamide derivatives are connected through the nitrogen atoms of central heterocyclic rings by a tether of bis-ethoxyethane chain.
Keywords :
Synthesis , Heterodimeric , Minor groove , Pyrrole , Imidazole.
Journal title :
Jordan Journal of Chemistry
Journal title :
Jordan Journal of Chemistry
