Title of article
Antibacterial Activity of Functionalized 1-(2,4-Dihydroxy-5- Substituted Phenyl)-3-Thienyl-Propane-1,3-Diones Bearing Potential O,O,S-Pharmacophores
Author/Authors
Sheikh, Javed National Environmental Engineering Research Institute (CSIR), India , Juneja, Harjeet RTM Nagpur University - Department of Chemistry, India , Ali, Parvez RTM Nagpur University - Department of Chemistry, India , Ingle, Vishwas RTM Nagpur University - Department of Chemistry, India
From page
107
To page
112
Abstract
A series of highly functionalized 1-(2 ,4 -dihydroxy-5 -substituted phenyl)-3-thienyl- propane-1,3-diones 3a-g have been produced upon Baker-Venkataraman rearrangement of 4- hydroxy-5-substituted-2-thienoyloxyacetophenones 2a-g using dimethylsulphoxide in NaOH. All the synthesized motifs 3a-g were confirmed by the spectroscopic analyses and evaluated for antibacterial efficacy against different pathogens.
Keywords
β , Diketones , Baker , Venkataraman rearrangement , Antibacterial activity , SAR.
Journal title
Jordan Journal of Chemistry
Journal title
Jordan Journal of Chemistry
Record number
2585134
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