Title of article :
Indium-Mediated Allylation of N-tert-Butylsulfinylaldimines with Dimethyl 2-[2-(Chloromethyl)allyl]malonate
Author/Authors :
Dema, Haythem K. University of Alicante - Faculty of Science, Institute of Organic Synthesis (ISO) - Department of Organic Chemistry, Spain , Foubelo, Francisco University of Alicante - Faculty of Science, Institute of Organic Synthesis (ISO) - Department of Organic Chemistry, Spain , Yus, Miguel University of Alicante - Faculty of Science, Institute of Organic Synthesis (ISO) - Department of Organic Chemistry, Spain
Abstract :
The reaction of N-tert-butylsulfinylaldimines 5 with dimethyl 2-[2-(chloromethyl)allyl]-malonate (10), in the presence of indium metal and sodium iodide, at room temperature for 72hours, led to the corresponding amino ester derivative 11. The reaction preceeded in high yields and in a total stereoselective fashion, a single diastereoisomer being always isolated.
Keywords :
N , tert , Butylsulfinylaldimines , Diastereoselective allylation , Indium , Amino esters.
Journal title :
Jordan Journal of Chemistry
Journal title :
Jordan Journal of Chemistry
