Author/Authors :
Akbari, Mohammad Esmaeil Cancer Research Center - Shahid Beheshti University of Medical Sciences - Tehran, Iran , Sayad, Soheila Department of Surgery - Firoozgar Clinical Research Development Center - Iran University of Medical Sciences - Tehran, Iran , Sayad, Saed Department of Chemical Engineering and Applied Chemistry - Data Mining Research Group - University of Toronto - Toronto - ON, Canada , Khayamzadeh, Maryam Cancer Research Center - Shahid Beheshti University of Medical Sciences - Tehran, Iran , Shojaee, Leila Cancer Research Center - Shahid Beheshti University of Medical Sciences - Tehran, Iran , Shormeji, Zeynab Faculty of Management and Medical Information - Iran University of Medical Sciences - Tehran, Iran , Amiri, Mojtaba Chemical Injuries Research Center - Baqiyatallah University of Medical Sciences - Tehran, Iran
Abstract :
Background. Breast cancer is the 5th leading cause of cancer death in Iranian women. This study analyzed 3010 women with breast
cancer that had been referred to a cancer research center in Tehran between 1998 and 2014. Methods. In this retrospective study, we
analyzed 3010 breast cancer cases with 32 clinical and paraclinical attributes. We checked the data quality rigorously and removed
any invalid values or records. The method was data mining (problem definition, data preparation, data exploration, modeling,
evaluation, and deployment). However, only the descriptive analyses’ results of the variables are presented in this article. To our
knowledge, this is the most comprehensive study on breast cancer status in Iran. Results. A typical Iranian breast cancer patient has
been a 40–50-year-old married woman with two children, who has a high school diploma and no history of abortion, smoking, or
diabetes. Most patients were estrogen and progesterone receptor positive, human epidermal growth factor (HER) negative, and P53
negative. Most cases were detected in stage 2 with intermediate grade. Conclusion. This study revealed original findings which can
be used in national policymaking to find the best early detection method and improve the care quality and breast cancer prevention in Iran.
