Author/Authors :
Komala, Ismiarni Universiti Putra Malaysia - Department of Chemistry, Malaysia , Rahmani, Mawardi Universiti Putra Malaysia - Department of Chemistry, Malaysia , Cheng Lian, Gwendoline Ee Universiti Putra Malaysia - Department of Chemistry, Malaysia , Mohd Ismail, Hazar Bebe university of malaya - Centre for Foundation Studies in Science, Malaysia , Sukari, Mohd Aspollah Universiti Putra Malaysia - Department of Chemistry, Malaysia , Rahmat, Asmah Universiti Putra Malaysia - Department of Health Science, Malaysia
Abstract :
Detailed extraction and separation of the aerial parts of Tetradium sambucinum (B.) Hartley have led to the isolation of decarine, rutaecarpine, aurantiamide acetate and 7-hydroxycoumarin. The structures of the compounds were established by one and two-dimensional H-and 13C-NMR as well other spectroscopic methods. The free radical scavenging and cytotoxic activities were assessed by DPPH assay and against two cancer cell lines, respectively.
Keywords :
Tetradium sambucinum , Evodia sambucina , decarine , rutaecarpine , aurantiamide acetate , 7 , hydroxycoumarin
