Author/Authors :
Yang, Chih-Chao Chang Gung University - College of Medicine, Kaohsiung Chang Gung Memorial Hospital - Department of Internal Medicine, Division of Nephrology, Taiwan , Chuang, Feng-Rong Chang Gung University - College of Medicine, Chang Gung Memorial Hospital - Department of Internal Medicine, Division of Nephrology, Taiwan , Wu, Chien-Hsing Chang Gung University - College of Medicine, Kaohsiung Chang Gung Memorial Hospital - Department of Internal Medicine, Division of Nephrology, Taiwan , Chen, Jin-Bor Chang Gung University - College of Medicine, Kaohsiung Chang Gung Memorial Hospital - Department of Internal Medicine, Division of Nephrology, Taiwan , Lee, Chih-Hsiung Chang Gung University - College of Medicine, Chang Gung Memorial Hospital - Department of Internal Medicine, Division of Nephrology, Taiwan , Lee, Chien-Te Chang Gung University - College of Medicine, Chang Gung Memorial Hospital - Department of Internal Medicine, Divisions of Nephrology, Taiwan
Abstract :
Objective: To report a potential salvage therapy for refractory renal cyst infection secondary to Salmonellaenterica serotype choleraesuis (S. choleraesuis).Clinical Presentation and Intervention: A 52-year-old male with autosomal dominant polycystic kidney disease undergoing hemodialysis experienced an episode of S. choleraesuis-related gastroenteritis subsequently complicated by bloodstream and refractory renal cyst infection with formation of multiple pyocysts. The patient was treated with intracystic indwelling diluted ciprofloxacin solution. Conclusion: In this patient, intracystic infusion of ciprofloxacin achieved a sufficient antibiotic level in infected renal cysts and hence completely eradicated S. choleraesuis. Therefore, intracystic antiobiotic infusion could be a potential salvage therapy for refractory renal cyst infection.
Keywords :
Autosomal dominant polycystic kidney disease , Intracystic ciprofloxacin , Renal cyst infection , Salmonella enterica serotype choleraesuis bacteremia