Author/Authors :
Yokus, Osman Okmeydani Education and Research Hospital - Department of Internal Medicine, Turkey , Uckurt, Yesim Sema Hospital, Turkey , Soner Demir, Ali Sema Hospital, Turkey , Kalyon, Semih Okmeydani Education and Research Hospital - Department of Internal Medicine, Turkey , Balcik, Ozlem Sahin Fatih University - Faculty of Medicine - Department of Internal Medicine, Turkey , Akdeniz, Derya Fatih University - Faculty of Medicine - Department of Internal Medicine, Turkey
Abstract :
Antiphospholipid syndrome is a disease presenting with arterial/ venous thrombosis and obstetrical complications. Pulmonary embolism is an important pulmonary complication of antiphospholipid syndrome, whereas, intra-alveolar hemorrhage is a rarely encountered manifestation. Hemophilia B is caused by factor IX deficiency that results in prolonged oozing after injuries and/or surgery, and delayed or recurrent bleeding prior to complete wound healing. Antithrombotic therapy may be used for recurrent hemostatic attacks in APS; but if there is a hemostatic defect, it may lead to serious bleeding complications. Here, we present a case of antiphospholipid syndrome accompanied by heterozygote methylene tetrahydrofolate reductase gene mutation (MTHFR) mutation and hemophilia B.
Keywords :
Antiphospholipid syndrome , Hemophilia B , Thrombosis , Bleeding.
