Author/Authors :
Duan, Jun China-Japan Friendship Hospital - Department of Ultrasound, China , Zheng, Chenglong Beijing University of Chinese Medicine - Beijing Gulou Hospital of Traditional Chinese Medicine, China , Gao, Kuo Beijing University of Chinese Medicine, China , Hao, Meina China-Japan Friendship Hospital - Department of Ultrasound, China , Yang, Lin China-Japan Friendship Hospital - Department of Ultrasound, China , Guo, Dandan China-Japan Friendship Hospital - Department of Ultrasound, China , Wu, Jingping China-Japan Friendship Hospital - Department of Ultrasound, China , Tian, Yan China-Japan Friendship Hospital - Department of Ultrasound, China , Song, Xueni China-Japan Friendship Hospital - Department of Ultrasound, China , Liu, Jian China-Japan Friendship Hospital - Department of Ultrasound, China , Guo, Shuwen Beijing University of Chinese Medicine, China , Murtaza, Ghulam COMSATS Institute of Information Technology - Department of Pharmaceutical Sciences, Pakistan , Zheng, Min China-Japan Friendship Hospital - Department of Ultrasound, China
Abstract :
Objective: One of the major complications of diabetes is blood vessel disease, termed angiopathy, which is characterized by abnormal angiogenesis. The objective of this study was to discuss the characteristics of lower limb vascular angiopathy and plaque formation in type 2 diabetes patients and finding its relevance to the carotid atherosclerotic plaque formation, thus directing the clinical diagnosis and treatment. Methods: The ultrasonography was used to monitor the patients with carotid artery and lower limb artery. Results: Compared with the control group, decreased blood flow to lower limb and lower limb angiopathy occurred more obviously in dorsal artery of foot than in popliteal artery. The study revealed that the detection rate of the prevalence of carotid atherosclerosis plaque and lower limb arterial plaque and the combination of plaque both carotid and lower limb arteries in diabetic patients was 369:342:296 (about 1.25:1.15:1) and that the prevalence of carotid plaque and lower limb arterial plaque in all subjects with plaque was 71.3%. The risk of plaque formation also had positive correlation with patient’s age. Color Doppler ultrasound had a clinical significance in the early diagnosis and curative effect observation in type 2 diabetes with lower limb angiopathy. The risk of simultaneous plaque formation in both carotid artery and lower extremity artery was greater in type 2 diabetes than that of control subjects, but they were not necessarily to occur simultaneously. The symptoms were inconspicuous in the early course of diabetes. Conclusion: The application of ultrasound monitoring in patients with carotid artery and lower limb artery might play a role in early warning, delaying the occurrence of macrovascular diseases, and slowing down the development of macroangiopathy such as cerebral infarction and diabetic foot and so on, thus providing a significant basis for clinical diagnosis and treatment.
Keywords :
Ultrasonography , Color Doppler , Lower extremity artery , Diabetic vascular disease
