Author/Authors :
Rakib, Tofazzal Department of Pathology and Parasitology - Chittagong Veterinary and Animal Sciences University - Chittagong, Bangladesh , Islam, Shafiqul Department of Pathology and Parasitology - Chittagong Veterinary and Animal Sciences University - Chittagong, Bangladesh , Mahbubur Rahman, Mohammad Department of Pathology and Parasitology - Chittagong Veterinary and Animal Sciences University - Chittagong, Bangladesh , Zonaed Siddiki, Amam Department of Pathology and Parasitology - Chittagong Veterinary and Animal Sciences University - Chittagong, Bangladesh , Chandra Sutradhar, Bibek Department of Medicine and Surgery - Chittagong Veterinary and Animal Sciences University - Chittagong, Bangladesh , Alamgir Hossain, Mohammad Department of Pathology and Parasitology - Chittagong Veterinary and Animal Sciences University - Chittagong, Bangladesh , uzzaman, Masud Department of Pathology and Parasitology - Chittagong Veterinary and Animal Sciences University - Chittagong, Bangladesh
Abstract :
Invasive ductal carcinoma is the most common invasive breast cancer in both women and pets, while the
mammary tumors are the second most frequent neoplasm in dogs. A 5 years old bitch was presented at Teaching
Veterinary Hospital of Chittagong Veterinary and Animal Sciences University, Bangladesh, having hard lump with
irregular borders at post umbilical region. The biopsy sample was taken followed by histopathology and ER, HER2/
neu, Ki67 immunostaining was done to know the type and cell origin of the tumour. Pleomorphism, increased mitotic
figure and metastasis were revealed in histopathology. The section gave higher response to ER, HER2/neu Ig where
response to Ki67 was low indicating luminal type A invasive ductal carcinoma. Grading tumours by immunostaining
aid in prognosis and therapy.
Keywords :
Invasive ductal carcinoma , Dog , ER , HER2/neu , Mammary gland
