Author/Authors :
izadi, vajihe isfahan university of medical sciences - food security research center, Isfahan, Iran , izadi, vajihe isfahan university of medical sciences - school of nutrition food science - department of community nutrition, Isfahan, iran , esmaillzadeh, ahmad isfahan university of medical sciences - school of nutrition food science - department of community nutrition, Isfahan, Iran , esmaillzadeh, ahmad tehran university of medical sciences - school of nutritional sciences and dietetics - department of community nutrition, Tehran, Iran , hashemipour, mahin isfahan university of medical sciences - child growth and development research center - department of pediatric endocrinology, Isfahan, Iran , surkan, pamela j. john hopkins university - bloomberg school of public health - department of international health, Baltimore, usa , azadbakht, leila tehran university of medical sciences - school of nutritional sciences and dietetics - department of community nutrition, Tehran, Iran , azadbakht, leila isfahan university of medical sciences - school of nutrition food science - department of community nutrition, Isfahan, Iran , azadbakht, leila tehran university of medical sciences - diabetes research center, endocrinology and metabolism clinical sciences institute, Tehran, iran , kelishadi, roya isfahan university of medical sciences - child growth and development research center, research institute for primordial prevention of non-communicable disease - department of pediatrics, Isfahan, Iran
Abstract :
Introduction: Limited information exists regarding the effects of high protein (HP) diets on cardiovascular disease (CVD) risk factors among overweight and obese children. Our aim was to determine the effects of an HP diet on anthropometric indexes and CVD risk factors among overweight and obese children. Methods: In a parallel randomized controlled trial, we recruited 50 overweight and obese children, aged 6-11 years, for a 10 week HP or control diet (protein, carbohydrate, fat: 25%, 45%, 30% in the HP diet vs. 15%, 55%, 30% in the control diet, respectively). Fasting blood glucose (FBG) serum insulin levels, lipid profiles, systolic and diastolic blood pressure (SBP and DBP), and anthropometric measurements were assessed using standard guidelines. Results: 86% of children completed the trial. Percent changes (PC) for anthropometric and biochemical variables were not significantly different between the two groups. The PC of serum triglyceride (TG) level was significantly decreased in the HP group compared to in the control group (PC: -10.16±4.30% vs.12.11±7.80%; P = 0.01) in the crude model, but not in the adjusted model. For other variables, we did not find any significant differences between the HP group and the controls. Conclusion: In the present study, we did not find any significant effect of adherence to an HP diet in improving anthropometric measurements or other CVD risk factors among obese and overweight children.
Keywords :
High Protein Diet , Cardiovascular Risk Factors , Children , Obesity , Overweight
