Prognostic value of normal exercise Tc-99m Sestamibi myocardial perfusion imaging in Karachi, Pakistan

Objective: To ascertain the hard event rate in local population with normal myocardial perfusion.Methods: The study, which was conducted from August 2006 to January 2007, included 300 patients with normal exercise myocardial perfusion scan (MPS). Patients were categorized according to their pre-test probabilities for CAD. Patients with low pre-test probability for CAD were 136 and ranked in group A, while group B constituted 164 patients who had intermediate to high pre-test probability.Results: During a follow-up of mean duration of 27 ± 3 months, an overall hard cardiac event rate of 1.02% was noted. However, a statistically non-significant difference between the survival rates of low and high pre-test probability groups was also observed.Conclusion: The study demonstrated good prognosis for patients with normal exercise myocardial perfusion scan