Author/Authors :
amanpour, sara kerman university of medical sciences - school of dentistry - department of oral and maxillofacial pathology, ايران , fardisi, sorena shiraz university of medical sciences - school of dentistry - department of oral and maxillofacial surgery, ايران , tabrizi, reza shahid beheshti university of medical sciences - school of dentistry - dept. of oral and maxillofacial surgery, ايران , zarei, mohammad reza kerman oral and dental diseases research center - department of oral medicine, ايران , raoof, maryam kerman university of medical sciences - neuroscience research center, institute of neuropharmacology - laboratory of molecular neuroscience, ايران , khatami, roya shahed university - school of dentistry - department of oral medicine, ايران
Abstract :
A rare case of squamous cell carcinoma ex pleomorphic adenoma in maxillary sinus is presented. The patient is a 50-year-old woman presenting with a slow-progressive swelling in left side of her face that she has noticed 2 years earlier. The lesion was not painful and caused asymmetry and mild exophthalmos. Microscopic examination revealed that the tumor was composed of two components; partly of a pleomorphic adenoma and partly of a squamous cell carcinoma. Immunohistochemical examination for Ki-67 and SMA and mucicarmin staining were also done and confirmed the diagnosis of carcinoma ex pleomorphic adenoma. There is no evidence of recurrence 12 months after operation.
Keywords :
Pleomorphic adenoma , Malignant transformation , Squamous cell carcinoma , Case report