Title of article :
Synthesis of Nitrogen Functional Derivatives of 5-substituted-6-azauracil as one of the Four Nucleobases in the Nucleic Acid of RNA
Author/Authors :
Kabirifard, H. islamic azad university - Department of Chemistry, ايران , Alimardani, Z. islamic azad university - Department of Chemistry, ايران , Ataeimehr, N. islamic azad university - Department of Chemistry, ايران , Rezai, G. islamic azad university - Department of Chemistry, ايران
Abstract :
3-Arylhydrazono-2,4-dioxo-4-phenylbutanoateshave been prepared by the coupling of benzoylpyruvate with aryldiazonium chlorides.Reactions ofthe 3-arylhydrazono-2,4-dioxo-4-phenylbutanoateswith 1-aminoguanidine, semicarbazide, and thiosemicarbazidegave5-substituted 2-imino-6-azauracil ( 3a ),6-azauracil ( 3b ), and 2-thio-6-azauracil ( 3c ), respectively. The analytical data of these compounds - IR, 1H, and ^13 C NMR spectral data - are reported.
Keywords :
Coupling , Benzoylpyruvate , Arylhydrazone , 1,2,4 , Triazin , 5 , one, 6 , Azauracil
Journal title :
Quarterly Journal of Applied Chemical Research (JACR)
Journal title :
Quarterly Journal of Applied Chemical Research (JACR)
