Author/Authors :
Korany, Reda M. S. Department of Pathology - Faculty of Veterinary Medicine - Cairo University, Giza, Egypt , Derbala, M. K. Animal Reproduction Research Institute, ARC, Giza, Egypt , Mosallam, T. E. Animal Reproduction Research Institute, ARC, Giza, Egypt , Fadel, M. Animal Reproduction Research Institute, ARC, Giza, Egypt , Aly, A. H. Animal Reproduction Research Institute, ARC, Giza, Egypt , Essmail, M. E. Animal Reproduction Research Institute, ARC, Giza, Egypt
Abstract :
Granulosa cell tumors (GCTs) found to be the most common ovarian tumor in mares. This work was
aimed to assess the GCT by different investigatory methods as, ultrasonography, hormonal profile and histopathology.
62 Arabian mares aged between 4- 15 years were admitted to hospital with various behavioral changes, these mares
examined physically, ultrasonographicaly and by assessment of hormonal profile, ovariectomy was indicated, gross
and histopathological evaluation of removed ovaries was performed. Ultrasonographic scanning encountered different
types of GCT, that appeared as honeycomb appearance, cystic, solid mass and mixed pattern. The hormonal profile
showed higher levels of AMH, progesterone, estrogen and testosterone compared with control group. Histopathologic
investigation ensured the presence of GCT in all examined cases with different tumor patterns, although the tumor
in all cases was benign. In conclusion, GCT in mares can be diagnosed by ultrasonography, hormonal assays and
histopathology. Most cases of GCTs are benign and most affected side is left one. The treatment of choice in case of
GCTs is ovariectomy.
Keywords :
GCTs , Arabian mares , Ultrasonography , Hormonal profile , Histopathology
