Unusual involvement of right ventricle in patient with Rosai–Dorfman disease

Rosai–Dorfman disease (RDD) is a benign form of histiocyte proliferation with unknown etiology that was first described by Rosai–Dorfman in 1969 (1). RDD is mostly presented with cervical lymphadenopathy, and also involves the extranodal system including skin, nasal cavity and paranasal sinuses, orbit, upper respiratory tract, and bone (2). RDD rarely involves the heart. There are only 19 reported cases of RDD in the literature, with none involving the right ventricle. In this case, we present RDD with the parotid gland, mediastinum, and cardiac involvement.