Video Capsule Endoscopy in the Assessment of Portal Hypertensive Enteropathy

Background. Te features of the portal hypertension enteropathy (PHE) vary from mild mucosal changes to varices with or without bleeding. Te prevalence and the development are not fully understood.Aim. Our aim is to examine the prevalence and the diferent manifestations of PHE using video capsule endoscopy (VCE). Methods. It is a single center retrospective study of patients with cirrhosis, who had VCE. Based on the published literature, we divided the PHE lesions into vascular lesions and mucosal lesions. Results. Of the 100 patients with cirrhosis that had a VCE study, the mean age was 62.82 years. Male gender was predominant (64%), while Caucasians represented 82% of the cohort. Te most common etiology of cirrhosis was chronic alcohol abuse followed by chronic hepatitis C virus and nonalcoholic steatohepatitis. VCE detected small bowel lesions in 71% of the patients while the features of PHE were found in 65% from the total cohort. AVMs and infammatory changes were the most common fndings, followed by bleeding. More than 50% of the lesions were vascular in nature.Te risk of fnding PHE in decompensated cirrhosis is twice that in compensated cirrhosis. Forty-fve patients had negative EGD exam for any active bleeding, esophageal varices, portal hypertensive gastropathy, or gastric varices. Of these, 69% had features of PHE in their VCE. Conclusions. VCE detected small bowel lesions in 71% of our cohort. Tere is a high prevalence of PHE in decompensated cirrhosis. Vascular lesions are the most common fnding in the small bowel of this population.