Retinal Microvascular Response to Short-Term Exposure to Particulate Matters As an Indicator of Cardiovascular Effects in Work Environments

Introduction: According to the literature, Central Retinal Arteriolar Equivalent (CRAE), Central Retinal Venular Equivalent (CRVE), and Artemio Venule Ratio (AVR) are three important markers in determining the changes of retinal artery. These markers are employed as an indicator of cardiovascular effects in workers. This study aimed to evaluate the changes in retinal micro vascular responses in workers exposed to shortterm exposure to particulate matters caused by occupational processes using CRAE, CRVE, and AVR markers. Materials and Methods: In this study, 96 workers exposed to jobrelated pollution in a tile and ceramic company were investigated. Fundus photos of these people were analyzed via ARIA software using the related protocols. The data were investigated employing Kolmogorov -Smirnov and MannWhitney tests as well as the correlation and regression tests. Results: No significant difference was observed in the ocular parameters of smokers and nonsmokers. Cardiovascular parameters had no significant correlation with CRAE and CRVE as well as breathable and inhalable dust; however, these parameters had a direct and significant correlation with AVR, PM10, and PM2.5 particles. Conclusion: The results did not show any changes in the retinal artery in workers who were exposed to jobrelated pollution. Moreover, no significant relationship was found between retinal artery changes and cardiovascular parameters. However, more largescale studies are needed to clarify the relationship of particulate air pollutants with CRAE, CRVE, and AVR changes.