Treatment Results of non-Hodgkin s Lymphoma Cases in Çukurova Region of Turkey

Purpose: We aimed to evaluate the clinicopathological characteristics and prognostic features of non-Hodgkin lymphoma (NHL) in pediatric patients in Çukurova Region, Turkey. Material and Methods: Histopathologically, 24 (63.2%) patients were diagnosed as Burkitt lymphoma, 12 (31.6%) patients were diagnosed as T-cell lymphoblastic lymphoma and 2 (5.2%) patients were diagnosed as diffuse large cell lymphoma. Patients were staged according to Murphy s classification in children. Treatment protocols of BFM-90 and LSA2L2 were applied to patients.Results: While mean age of 38 patients with NHL was 75.3±41.5 months , 12 (31.6%) patients were female and 26 (68.4%) patients were male. One (2.6%) patient was evaluated as stage I, 8 (21.1%) patients were as stage II, 18 (47.4%) patients were as stage III and, 11 (28.9 %) patients were as stage IV. Overall survival for 5 years was found as 71%. When overall survival were estimated based on histopathological study, 93%, 56% and %50 were found for T-cell lymphoblastic lymphoma, Burkitt lenfoma and diffuse large cell group, respectively. Conclusion: The prognosis of NHL cases followed by our clinic varied according to the stage and histopathological type. Although most of our cases were Burkitt or stage III-IV lymphomas, the clinical response to the treatment protocols were similar to the literature.