FeCl3/ AgOTf Catalyzed Hydroarylation Reactions of Aryl-substitutedAlkynes with Different Electron-rich Arenes

There are many synthetic methods for the direct formation of carbon-carbon bond between arenes and alkynes. Metal-catalyzed hydroarylation reaction is one of the synthetic methods for the direct formation of new carbon-carbon bond between arenes and alkynes. The hydroarylation reaction of aryl-substituted alkynes with arenes proceeded smoothly in the presence of FeCl3/AgOTf catalyst system in a mixed solvent of trifluoroacetic acid and dichloromethane at 30ºC and yielded aryl-substituted alkenes in moderate to high yields. Electron rich arenes gave high yields whereas the relatively less electron rich arenes gave norminal yields.