The Use of Biological Antimycotoxin in Amelioration of Ochratoxicosis in Broiler Chicken and Decrease of Toxin Residues in the Breast Muscles

Ochratoxin A (OTA) is one of the most important and deleterious mycotoxins. The present study explored the effects of OTA on broiler by detection of the hematological and immunological changes, as well as performing kidney function tests and determining its residues in the breast muscle with a trial using biological anti-mycotoxin to eliminate OTA residues and their harmful effects. Sixty broiler chickens were used for detecting the effects of OTA. The birds were divided into three equal groups. The first group was kept as control, the second was fed with a ration containing 0.2 mg /kg OTA, and the third one was fed with a ration containing 0.2 mg /kg OTA and biological anti-mycotoxin (Bio-Stress) (1gm/liter of drinking water) from one day old until the appearance of OTA toxicity symptoms in the second gp., which was at 32 days-old. The present study revealed anemia and leucopenia in the OTA-treated group, with a significant decrease in lymphocyte level, phagocytic activity, lysozyme concentration, total protein, serum albumin, globulin; and alph-1, alpha-2, and beta, gamma globulins and calcium levels; but serum A/G ratio, creatinine, uric acid, and inorganic phosphorus levels were significantly increased. Improvement of most of these parameters occurred by the use of biological anti-mycotoxin.We detected significantly high levels of ochratoxin residue in the breast muscle of the birds treated with OTA only as compared with the control group and that treated with OTA and anti-mycotoxin.