Title of article
Spectrophotometric Determination of Mefenamic Acid in Pharmaceutical Preparations
Author/Authors
dikran, sarmad b . university of baghdad - college of education for pure science (ibn al-haitham) - department of chemistry, Iraq , al-joboury, moen i. university of baghdad - college of education for pure science (ibn al-haitham) - department of chemistry, Iraq , mohammed, alaa k. university of baghdad - college of education for pure science (ibn al- haitham) - department of chemistry, Iraq , naser, ahmed s. university of tikrit - college of science - department of chemistry, Iraq
Pages
11
From page
339
To page
349
Abstract
A simple, accurate and precise spectrophotometric method has been proposed for the
determination of Mefenamic acid(MA) in dosage forms. Proposed method based on the
reaction of cited drug with 1,2-Naphthoquinone-4-Sulfonic sodium (NQS). The optimum
experimental condition have been studied. Beer's Law is obeyed in the concentration range
0.5-10.0 µg/mL at 450nm with detection limit of 0.189µg/mL. Effect of pH, reaction time,
and volume of NQS on the determination of Mefenamic acid, have been examined. The
proposed method has been successfully applied for the determination of Mefenamic acid in
pharmaceutical preparations.
Keywords
1,2-Nphatha quinona-4-Sulfonic sodium , Mefenamic acid , Spectrophotometric
Journal title
Ibn Alhaitham Journal For Pure and Applied Science
Serial Year
2014
Journal title
Ibn Alhaitham Journal For Pure and Applied Science
Record number
2602442
Link To Document