Contrast-induced acute kidney injury/contrast-induced nephropathy may be related to additional risk factors

We read with interest the article entitled “Impact of continuation of metformin prior to elective coronary angiography on acute contrast nephropathy in patients with normal or mildly impaired renal functions” by Oktay et al. (1) published in the Anatolian Journal of Cardiology. The authors investigated the association of metformin treatment with contrast-induced acute kidney injury/contrast-induced nephropathy (CI-AKI/CIN). In this study, they concluded that periprocedural metformin treatment in patients with type 2 diabetes mellitus undergoing elective coronary angiography (CAG) with normal or mildly impaired renal functions (eGFR >60 mL/min/1.73 m2 ) was reliable with respect to the development of CI-AKI/CIN and lactic acidosis.