Title of article :
Massive Tibial Bone Regeneration with Autologous Peripheral Blood Stem Cells using Ilizarov Bone Transport: A Case Report
Author/Authors :
KY, Saw Department of Orthopaedic Surgery - Kuala Lumpur Sports Medicine Centre - Kuala Lumpur, Malaysia , R, Gill Department of Orthopaedic Surgery - Kuala Lumpur Sports Medicine Centre - Kuala Lumpur, Malaysia , TC, Low Department of Orthopaedic Surgery - Kuala Lumpur Sports Medicine Centre - Kuala Lumpur, Malaysia
Abstract :
This is a case report of a Gustilo-Anderson Type IIIB comminuted open right tibial fracture with massive bone loss, complicated by methicillin-resistant Staphylococus aureus (MRSA) infection. Non-viable and contaminated
bony fragments were removed and infected bone resected.
Soft tissue coverage and antibiotics were effective against
the MRSA infection. A unifocal bone transport with the
Ilizarov method regenerated 13cm of the missing tibia.
Autologous peripheral blood stem cells (PBSC) injections into the osteogenesis site boosted bone regeneration and consolidation with a shortened Bone Healing index (BHI) of 23 days/cm.
Keywords :
massive bone loss , bone regeneration , Bone Healing index , peripheral blood stem cells , Ilizarov
Journal title :
Malaysian Orthopaedic Journal
