Title of article :
Clinical and PSG Characteristics of Children with Mild OSA and Respiratory Events Terminated Predominantly with Arousal
Author/Authors :
Wu, Yunxiao Beijing Key Laboratory of Pediatric Diseases of Otolaryngology Head and Neck Surgery - Beijing Pediatric Research Institute - Beijing Childrens Hospital - Capital Medical University - National Center for Children’s Health, Beijing, China , Zheng, Li Department of Otolaryngology Head and Neck Surgery - Beijing Children’s Hospital - Capital Medical University - National Center for Children’s Health, Beijing, China , Wu, Panting Department of Respiratory Medicine - Beijing Children’s Hospital - Capital Medical University - National Center for Children’s Health, Beijing, China , Tang, Yufen Department of Respiratory Medicine - Beijing Children’s Hospital - Capital Medical University - National Center for Children’s Health, Beijing, China , Xu, Zhifei Department of Respiratory Medicine - Beijing Children’s Hospital - Capital Medical University - National Center for Children’s Health, Beijing, China , Ni, Xin Department of Otolaryngology Head and Neck Surgery - Beijing Children’s Hospital - Capital Medical University - National Center for Childrens Health, Beijing, China
Abstract :
Objective. To analyze the clinical and polysomnographic characteristics in children with mild OSA and respiratory events
terminated predominantly with arousal. Methods. Children aged 3–10 yrs who had mild obstructive sleep apnea (OSA) were
enrolled. All children underwent polysomnography, and patients’ data were collected by using sleep-related breathing disorders
(SRBD) questionnaire and OSA-18 quality of life questionnaire. Results. In total, five hundred and seventy-seven children were
eligible. Children in arousal predominant group were younger and showed a lower rate of male and obesity. Compared with that of
the nonarousal predominant group, the total arousal index, arousal index related to respiratory event, the percentage of NREM
stage 1 (N1%), the fraction of respiratory events that were hypopnea, and the mean and minimum oxygen saturation in the arousal
predominant group were significantly greater. -e percentage of NREM stage 3 (N%), index of obstructive, central, mixed apnea,
the fraction of respiratory events that were obstructive, and central and mixed apnea were significantly lower in arousal predominant group. Conclusion. Children with mild OSA in the arousal predominant group had specific characteristics, including
younger age, lower rate of male and obesity, worse sleep architecture, higher rates of hypopnea events, and better oxygenation.
-is trial is registered with NCT02447614.
Keywords :
Characteristics Children , Clinical Characteristics , Mild OSA , Respiratory Events
Journal title :
Canadian Respiratory Journal
