Cotard’s Syndrome in a Patient with Schizophrenia:Case Report and Review of the Literature

Jules Cotard described, in 1880, the case of a patient characterized by delusions of negation, immortality, and guilt as well asmelancholic anxiety among other clinical features. Later this constellation of symptoms was given the eponym Cotard’s syndrome,going through a series of theoretical vicissitudes, considering itself currently as just the presence of nihilistic delusions. Thepresentation of the complete clinical features described by Cotard is a rare occurrence, especially in the context of schizophrenia.Here we present the case of a 50-year-old male patient with schizophrenia who developed Cotard’s syndrome. The patient wastreated with aripiprazole, showing improvement after two weeks of treatment. A review of the literature is performed about this case